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Motif: AUF1_binding (RM00002)

Description: AUF1 binding site

Summary

Wikipedia annotation Edit Wikipedia article

The Rfam group coordinates the annotation of Rfam data in Wikipedia. This motif is described by a Wikipedia entry entitled HNRPD. More...

This page is based on a wikipedia article. The text is available under the Creative Commons Attribution/Share-Alike License.

Alignments

You can either download the motif alignment or view it directly in your browser window. More...

Formatting options

You can view or download motif alignments in several formats. Check either the "download" button, to save the formatted alignment, or "view", to see it in your browser window, and click "Generate".

Alignment format:
Download/view:

Family matches

There are 3 Rfam families which match this motif.

This section shows the families which have been annotated with this motif. Users should be aware that the motifs are structural constructs and do not necessarily conform to taxonomic boundaries in the way that Rfam families do. More...

Original order Family Accession Family Description Number of Hits Fraction of Hits Sum of Bits Image
3 RF00539 Small nucleolar RNA Me28S-Cm788 4 0.800 75.2 Match Image
3 RF01267 Small nucleolar RNA snR37 3 0.333 55.2 Match Image
3 RF03802 MIR5649 microRNA precursor family 2 1.000 37.4 Match Image

References

This section shows the database cross-references that we have for this Rfam motif.

Literature references

  1. Mazan-Mamczarz K, Kuwano Y, Zhan M, White EJ, Martindale JL, Lal A, Gorospe M Nucleic Acids Res. 2009;37:204-14. Identification of a signature motif in target mRNAs of RNA-binding protein AUF1. PUBMED:19033365

External database links

Curation and motif details

This section shows the detailed information about the Rfam motif. We're happy to receive updated or improved alignments for new or existing families. Submit your new alignment and we'll take a look.

Curation

Seed source Published; PMID:14981256
Structure source N/A
Type Specific Recognition Motif
Author Gardner PP
Alignment details
Alignment Number of
sequences
Average length Sequence
identity (%)
seed 8 33.88 35

Model information

Build commands
cmbuild -F CM SEED
cmcalibrate --mpi --seed 1 CM
Gathering cutoff 16.0
Covariance model Download the Infernal CM for the motif here