SNORD105 clan

The SNORD105 clan contains the RNA families SNORD105 and snoU105B. Homology between these families has been established in the published literature [1,2]. The following bioinformatic methods were used to confirm the relationship between these families: CMSEARCH, HMMER3 and PRC [3,4,5].

This clan contains 2 families and the total number of sequence regions in the clan is 278.

Literature references

1. Lestrade L, Weber MJ;, Nucleic Acids Res. 2006;34:D158-D162.: snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. 16381836
2. Yang JH, Zhang XC, Huang ZP, Zhou H, Huang MB, Zhang S, Chen YQ, Qu LH, Nucleic Acids Res. 2006;34:5112-5123.: snoSeeker: an advanced computational package for screening of guide and orphan snoRNA genes in the human genome. 16990247
3. Nawrocki EP, Kolbe DL, Eddy SR, Bioinformatics. 2009;25:1335-7.: Infernal 1.0: inference of RNA alignments. 19307242
4. Eddy SR, PLoS Comput Biol. 2008;4:e1000069.: A probabilistic model of local sequence alignment that simplifies statistical significance estimation. 18516236
5. Madera M, Bioinformatics. 2008;24:2630-2631.: Profile Comparer: a program for scoring and aligning profile hidden Markov models. 18845584

Members

This clan contains the following 2 member families:

SNORD105 snoU105B

This tool allows you to view the secondary structure images of two clan members side-by-side. Choose the family structures using the two drop-down menus below.

The table below shows the number of occurrences of each family throughout the sequence database. In brackets beside each number is the percentage of the total number of sequence hits for the clan that are represented by this family. The rightmost column provides a link to the alignments tab for each family.

Rfam family	Num. regions	Alignment
snoU105B (RF01173)	132 (47.5%)	View
SNORD105 (RF00584)	146 (52.5%)	View