SNORA74 clan

The SNORA74 clan contains the RNA families SNORA74 and snR191. Researchers at the human snoRNA database (snoRNABase) have established that the following human and S. cerevisiae snoRNAs target modifications on orthologous positions of the ribosome: SNORA74 and snR191 [1]. The following bioinformatic methods were used to confirm the relationship between these families: HMMER3 [2].

This clan contains 2 families and the total number of sequence regions in the clan is 1,817.

Literature references

1. Lestrade L, Weber MJ;, Nucleic Acids Res. 2006;34:D158-D162.: snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. 16381836
2. Eddy SR, PLoS Comput Biol. 2008;4:e1000069.: A probabilistic model of local sequence alignment that simplifies statistical significance estimation. 18516236

Members

This clan contains the following 2 member families:

SNORA74 snR191

External database links

External sites:

1: http://www-snorna.biotoul.fr/human_yeast/

This tool allows you to view the secondary structure images of two clan members side-by-side. Choose the family structures using the two drop-down menus below.

The table below shows the number of occurrences of each family throughout the sequence database. In brackets beside each number is the percentage of the total number of sequence hits for the clan that are represented by this family. The rightmost column provides a link to the alignments tab for each family.

Rfam family	Num. regions	Alignment
snR191 (RF01263)	469 (25.8%)	View
SNORA74 (RF00090)	1,348 (74.2%)	View